pentobarbital will lower the level or effect of ondansetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. No dosage adjustment for ondansetron is suggested for patients on these drugs.pentobarbital will minimize the level or result of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Ke
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